Hippocrates said,

"The brain, and the brain alone, is the source of our pleasures, joys, laughter, and amusement, as well as our sorrow, pain, grief, and tears. It is especially the organ we use to think and learn, see and hear, to distinguish the ugly from the beautiful, the bad from the good, and the pleasant from the unpleasant. The brain is also the seat of madness and delirium, of the fears and terrors which assail by night or by day, of sleeplessness, awkward mistakes and thoughts that will not come, of pointless anxieties, forgetfulness and eccentricities." Hippocrates, 400 BC

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